Protective Effects of Celastrol on Diabetic Liver Injury via TLR4/MyD88/NF-κB Signaling Pathway in Type 2 Diabetic Rats

Table 2

Glucose and islet function parameters after 8-week high fat feeding.

Group	FPG (mmol/L)	TG (mmol/L)	TC (mmol/L)	FINS (mIU/L)	HOMA-IR	HOMA-β
NC	5.7 ± 0.5	1.3 ± 0.4	2.0 ± 0.2	25.1 ± 4.1	6.5 ± 1.7	230.7 ± 28.7
High-fat	6.1 ± 0.7	3.0 ± 0.7	3.2 ± 0.5	31.6 ± 6.1	8.6 ± 2.3	259.8 ± 42.1

FPG: fasting plasma glucose; TG: triglycerides; TC: total cholesterol; FINS: fasting insulin; IR: insulin resistance. Data are expressed as mean ± SEM, P < 0.05 versus NC group.