An Immunomodulatory Device Improves Insulin Resistance in Obese Porcine Model of Metabolic Syndrome

Figure 3

Ossabaw pigs (MET03 and MET04) were started on a high caloric, atherogenic diet at 2 months of age to incite development of metabolic syndrome, including insulin resistance. GTT was performed pre Rx course (), day 1 after Rx course (●), week 1 after Rx course (□), and week 2 post Rx course (■). A metabolic score (a), calculated by insulin × glucose levels obtained during GTT, indicated improved insulin sensitivity was conferred by SCD therapy. The effect persisted for 2 weeks after the SCD Rx course. The glucose levels (b) and insulin levels (c) used to generate the metabolic score are also shown. Average of 3 SCD Rx courses that consisted of three 6-hour SCD treatments in one week is shown ± SE ().

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(b)

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