Lactic Acidosis in Diabetic Population: Is Metformin Implicated? Results of a Matched Case-Control Study Performed on the Type 2 Diabetes Population of Grenoble Hospital University

Table 2

Conditional logistic regression of covariates ().

Variables	Matched OR	CI 95%	value
Chronical medical condition
No CKD	1	—	—
CKD mild-moderate	0.36	[0.19–0.69]	0.002
CKD severe-end stage	1.62	[0.62–4.25]	0.325
Hepatocellular dysfunction	6.51	[2.78–15.25]	<0.001
Concomitant therapies
Metformin	1.27	[0.73–2.22]	0.390
Intercurrent diseases
AKI	9.58	[5.24–17.47]	<0.001
Acute respiratory failure	9.34	[4.76–18.32]	<0.001
Acute decompensated heart failure	3.55	[1.84–6.84]	<0.001
Sepsis	8.28	[4.28–15.99]	<0.001