The Expanded Bead Size of Corneal C-Nerve Fibers Visualized by Corneal Confocal Microscopy Is Associated with Slow Conduction Velocity of the Peripheral Nerves in Patients with Type 2 Diabetes Mellitus

Figure 2

The representative beads in the original CCM images (a), images simply magnified 5 times by Photoshop (b), and images enlarged 5 times with smoothing by the S-Spline Max algorithm (c) in a control subject (1, male, 56 years, NDS: 0), patient without neuropathy (2, male, 52 years, NDS: 1), patient with mild neuropathy (3, male, 54 years, NDS: 5), patient with moderate neuropathy (4, male, 56 years, NDS: 7), and patient with severe neuropathy (5, male, 57 years, NDS: 9).