Research Article

The Expanded Bead Size of Corneal C-Nerve Fibers Visualized by Corneal Confocal Microscopy Is Associated with Slow Conduction Velocity of the Peripheral Nerves in Patients with Type 2 Diabetes Mellitus

Table 2

Summary of corneal nerves morphological parameters in control subjects, type 2 diabetic patients, and their subgroups stratified by the stages of neuropathy.

Corneal nerves morphological parameters Control subjects Patients with type 2 diabetes
All type 2 diabetic patients Stratified by stages of neuropathy
No neuropathy
NDS (0–2)
Mild
NDS (3–5)
Moderate
NDS (6–8)
Severe
NDS (9-10)

Corneal nerve fiber density (CNFD) (no/mm2)
Corneal nerve fiber length (CNFL) (mm/mm2)
Corneal nerve branch density (CNBD) (no/mm2)
Tortuosity grade (TG)
Beading frequency (BF) (number/0.1 mm)
Bead size (BS) (μm2)

Data are expressed as mean ± standard error of the mean (SEM) in control subjects, type 2 diabetic patients, and their subgroups stratified by the Neuropathy Disability Score (NDS). compared with control subjects, compared with patients without neuropathy, compared with control subjects, and compared with control subjects.