Changes of Regulatory T Cells and of Proinflammatory and Immunosuppressive Cytokines in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis

Table 3

Characteristics of studies about TNF- (pg/mL) included in this meta-analysis.

Author	Year	Country	Case				Control				NOS score
			SZ	M/F	Mean	SD	SZ	M/F	Mean	SD
Plomgaard [34]	2007	Denmark	96	72/24	2.72	0.8	103	70/33	2.4	0.54	8
Yaturu [68]	2008	USA	50	NR	4	0.36	59	NR	3.4	0.29	7
Yaturu [68]	2008	USA	26	NR	4.2	0.47	39	NR	3.2	0.32	8
Lin [69]	2015	China	42	20/22	5.49	1.48	30	14/16	3.46	0.58	8
Lin [69]	2015	China	45	25/20	6.82	2.97	30	14/16	3.46	0.58	8
Volpe [35]	2014	Brazil	29	10/19	78.7	32.7	16	5/11	58.5	29.5	7
Yeo [36]	2010	Korea	55	27/28	1.5	0.95	488	257/231	1.1	0.31	7
Lukic [38]	2014	Serbia	30	NR	1.53	0.42	15	NR	0.71	0.3	8
Lukic [38]	2014	Serbia	30	NR	1.54	0.41	15	NR	0.71	0.3	8
Daniele [45]	2014	USA	17	13/4	2.5	0.3	15	7/8	1.5	0.3	7

DM: diabetes mellitus; SZ: sample size; M/F: man/female; SD: standard deviation; NR: not reported. T2DM with complication and data (mean ± SD) converted from mean (95% CI).