Exenatide Activates the APPL1-AMPK-PPARα Axis to Prevent Diabetic Cardiomyocyte Apoptosis

Table 1

Metabolic parameters of rats.

Groups	Body weight; (g)	FBG; (mmol/L)	Fins; (mU/L)	TG; (mmol/L)	TC; (mmol/L)	Adiponectin; (g/L)	HOMA-IR	HMW-adiponectin; (g/L)
Control ()	318.1 ± 6.9^&	4.96 ± 0.25^&	21.85 ± 2.30	0.34 ± 0.04^&	1.32 ± 0.04^&	0.52 ± 0.06^&	4.81 ± 0.48^&	0.43 ± 0.11^&
D ()	457.8 ± 25.0	7.43 ± 0.83	21.37 ± 1.60	0.78 ± 0.06	2.16 ± 0.07	0.47 ± 0.04	7.35 ± 0.74	0.34 ± 0.09
DI ()	450.6 ± 6.0	5.23 ± 0.34	25.66 ± 1.88	0.75 ± 0.07	2.15 ± 0.07	0.47 ± 0.03	5.81 ± 0.37^&	0.38 ± 0.08
DE ()	318.7 ± 10.7^&	5.10 ± 0.33	23.20 ± 1.47	0.52 ± 0.04^&	1.30 ± 0.08^&	0.76 ± 0.03	5.27 ± 0.59^&	0.70 ± 0.07

FBG, fasting blood glucose; FFA, free fatty acids; FIns, fasting plasma insulin; kg twice daily; Control, rats fed normal chow diet; TC, total cholesterol; TG, triglyceride. Data are means ± s.e.
Compared with the Control group: < 0.05; compared with the D group: ^& < 0.05.