Research Article

Impact of Real-Time Continuous Glucose Monitoring Use on Glucose Variability and Endothelial Function in Adolescents with Type 1 Diabetes: New Technology—New Possibility to Decrease Cardiovascular Risk?

Table 3

Glucose variability depending on the initial HbA1c level.

HbA1c before the study
<7.5%≥7.5%

HbA1c
(%)
Before the study
After the study
7.25 ± 0.19
6.73 ± 0.47
0.006
9.88 ± 1.22
9.33 ± 1.62
0.003

Mean glucose
(mg/dL)
1st week
Last week
127.75 ± 9.84
126.75 ± 23.26
0.8
178.28 ± 29.90
149.31 ± 8.12
<0.001

Mean glucose SD (mg/dL)1st week
Last week
46.75 ± 6.94
44.75 ± 3.49
0.286
64.88 ± 13.57
55.75 ± 14.95
0.003

AUC > 140 mg/dL1st week
Last week
14.75 ± 6.94
13.00 ± 3.52
0.157
50.46 ± 24.33
28.29 ± 17.65
<0.001

AUC < 70 mg/dL1st week
Last week
0.98 ± 0.46
0.68 ± 0.28
0.203
0.49 ± 0.61
0.58 ± 0.62
0.957

Max glucose
(mg/dL)
1st week
Last week
279.75 ± 25.93
291.50 ± 14.92
0.14
375.26 ± 70.36
339.13 ± 71.90
<0.001

Min glucose (mg/dL)1st week
Last week
42.75 ± 1.75
48 ± 5.45
0.045
52.25 ± 13.17
47.37 ± 6.65
0.005

FMD (%)Before the study
After the study
16.25 ± 4.32
27.81 ± 6.49
0.002
9.57 ± 6.44
13.89 ± 6.43
<0.001

Results of RT-CGM are presented as mean ± SD.
: significant difference between two subgroups, considering the same time sensor usage (first or last week).