Oxidative Damage to the Salivary Glands of Rats with Streptozotocin-Induced Diabetes-Temporal Study: Oxidative Stress and Diabetic Salivary Glands

Table 1

The body weight, salivary unstimulated and stimulated flow rate, and the concentrations of plasma: insulin, glucose, free fatty acids, and pH of the control and streptozotocin-diabetic rats.

	Body weight (mg); M (min–max)	Salivary flow rate (L/min); M (min–max)		Insulin (ng/mL); M (min–max)	Glucose (mg/dL); M (min–max)	FFA (nmol/mL); M (min–max)	pH; M (min–max)
		UWS	SWS
C1	262.5 (223−279)	0.35 (0.2−0.56)	88.6 (75.9−130.2)	0.854 (0.799−1.456)	95.25 (76.53−99.74)	97.77 (74.39−103.87)	7.71 (7.7−7.9)
C2	282.5 (264−297)	0.36 (0.22−0.61)	86.4 (70.2−109.8)	1.066 (0.991−1.682)	97.86 (80.26−102.47)	91.56 (88.77−96.72)	7.71 (7.6−7.94)
DM1	230.5 (201−260)	0.32 (0.06−0.52)	63.79 (59.94−78.7)	0.0	237 (129−255)	156.43 (133.65−198.66)	7.71 (7.49−7.9)
DM2	227.5 (209−250)	0.27 (0.067−0.91)	52.7 (48.56−69.24)	0.0	548.02 (425.38−594.33)	162.98 (143.52−186.52)	7.71 (7.68−7.93)
(C1 : C2)	<0.05 (↑)	ns	ns	ns	ns	ns	ns
(DM1 : DM2)	ns	ns	ns	ns	<0.005 (↑)	ns	ns
(C1 : DM1)	<0.05 (↓)	ns	<0.05 (↓)	<0.000005 (↓)	<0.005 (↑)	<0.005 (↑)	ns
(C2 : DM2)	<0.05 (↓)	<0.05 (↓)	<0.05 (↓)	<0.000005 (↓)	<0.0005 (↑)	<0.005 (↑)	ns

C1: control group in the first week of the experiment, C2: control group in the second week of the experiment, DM1: diabetic group in the first week of the experiment, DM2: diabetic group in the first second of the experiment, SWS: stimulated whole saliva, UWS: unstimulated whole saliva, insulin: plasma insulin concentration, glucose: plasma glucose concentration, FFA: plasma free fatty acids concentration, M: median, min: minimum, max: maximum, ns: not significant, : statistical significance < 0.05, (↓): decrease, and (↑): increase.