Research Article
Modeling and Measurement of Correlation between Blood and Interstitial Glucose Changes
Figure 1
Theoretical model and simulation of correlation of blood and ISF glucose changes. (a) Mathematical equations derived from Starling equation and Fick’s laws for study of the relationship between blood and interstitial fluid (ISF) glucose changes. (b) Computer simulation generated time courses of glucose concentration changes in blood and ISF. The solid line represents blood glucose changes. The other dashed lines represent the ISF glucose changes after transcapillary transport through the capillary walls. Glucose concentration changes were simulated by the theoretical model with various diffusion distances () of 5, 15, and 25 μm. BG and ISFG represent blood and ISF glucose, respectively.
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