Par-4/NF-κB Mediates the Apoptosis of Islet β Cells Induced by Glucolipotoxicity

Table 2

The insulin secretion, Par-4 secretion, apoptosis rate, and protein expression of GRP78 and Par-4 of each group.

	C	C + Par-4	C − Par-4	H	H + Par-4	H − Par-4
Insulin (mIU/L)	6.67 ± 0.24	6.43 ± 0.30	6.65 ± 0.36	3.60 ± 0.20	2.29 ± 0.08	4.48 ± 0.26
Par-4 (mg/L)	70.05 ± 14.18	71.78 ± 19.38	67.60 ± 16.32	388.18 ± 18.43	766.22 ± 16.15	164.58 ± 16.63
Apoptosis rate (%)	2.88 ± 1.25	3.13 ± 1.55	2.13 ± 1.13	45.38 ± 7.91	62.75 ± 10.55	31.63 ± 6.00
GRP78	0.14 ± 0.01	0.14 ± 0.04	0.15 ± 0.03	0.89 ± 0.05	1.18 ± 0.13	0.60 ± 0.10
Par-4	0.81 ± 0.03	1.11 ± 0.03	0.63 ± 0.03	1.67 ± 0.10	2.22 ± 0.08	0.91 ± 0.04

Compared with H group; .
Compared with H − Par-4 group; .
Compared with H + Par-4 group; .