Review Article

Prevalence of Oral Mucosal Disorders in Diabetes Mellitus Patients Compared with a Control Group

Table 2

Confounding factors of selected studies.

Guggenheimer et al., 2000 [20]Saini et al., 2010 [21]Bastos et al., 2011 [22]Mohsin et al., 2014 [23]

TobaccoCases
Now, 19.4%
Ever, 37.5%
Controls
U
ExcludedCases
25 (17.2%)
Controls
30 (27%)
U

Other drugs takenCases
Cardiovascular agents, 19.8%,  
Immunosuppressants, 2.7%,  
Anticonvulsants, 2.7%,  
Thyroid supplements, 8.4%,  
Antimicrobials, 10.4%
Unknown, 5.2%
Controls
Cardiovascular agents, 6%
Immunosuppressants, 0.4%
Anticonvulsants, 0.4%
Thyroid supplements, 1.1%
Antimicrobials, 8.6%
Unknown, 7.1%
Cases
Cardiovascular agents, 22.4%
Antibiotics, 2.4%
NSAID, 3.3%
Antiasthmatic drugs, 1.4%
Others, 2.4%
Controls
Cardiovascular agents, 10%
Antibiotics, 1%
NSAID, 1.4%
Antiasthmatic drugs, 1.7%
Others, 1.7%
39.2% taking a daily medication, of which 73.3% were antihypertensives and 56% were antidepressantsU

Dentures usersCases
Complete or partial dentures, 12.3%,  
Controls
Complete or partial dentures, 3%
UUU

DM diagnosisUUControls: excluded by fasting blood glucose levelUUControls: excluded by fasting blood glucose level

Glycosylated hemoglobin (HbA1c)11 ± 0.18,49 ± 2,25
Good (<7.5), 172 (41%)
Moderate (7.6–8.9), 92 (21.9%)
Poor (>9), 156 (37.1%)
Adequate (<7): 38 (26%)
Inadequate (≥7): 108 (74%)
U

Diabetic complicationsNephropathy, 23.2%
Neuropathy, 26.9%
Retinopathy, 44.4%
Peripheral vascular disease, 10.6%
14.5%
U
65 (44.5%)
Nephropathy, 20.3%
Neuropathy, 16.5%
Retinopathy, 63.2%
Excluded

U: unspecified.