Review Article

Silymarin in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Table 2

Side effects.

StudySilymarin groupPlacebo
MeanSDMeanSD

Velussi et al. 1997 [26] 2.16 ep/pac/an hypoglycemic event 2.2 ep/pac/an hypoglycemic event
No side effectsā€‰

Huseini et al. 2006 [28]Not reportedā€‰

Hussain 2007 [29]No side effects

Fallahzadeh et al. 2012 [19] Nausea and vomiting3 (10%)28Nausea and vomiting2 (6.7%)28
Headache2 (6.7%)28Headache0 (0%)28
Dyspepsia and bloating1 (3.3%)28Dyspepsia and bloating0 (0)28

Ebrahimpour Koujan et al., 2015 [30]No side effects