Myocardial Perfusion and Function Are Distinctly Altered by Sevoflurane Anesthesia in Diet-Induced Prediabetic Rats

Figure 3

Effect of sevoflurane on systolic function in prediabetic rats. Systolic function, as represented by the fractional shortening (a) and fractional area change (b), measured with echocardiography in rats fed a control diet (CD) or western diet (WD) for 8 weeks during baseline conditions and after 5 minutes of sevoflurane exposure. Data are expressed as mean ± SD, ; two-way ANOVA with Bonferroni post hoc analyses, diet effect, sevoflurane effect.

(a)

(b)