Effect of Ranirestat on Sensory and Motor Nerve Function in Japanese Patients with Diabetic Polyneuropathy: A Randomized Double-Blind Placebo-Controlled Study

Table 4

Changes from baseline in the individual nerve amplitudes.

		Ranirestat; ()	Placebo; ()	values
Sensory nerve amplitude (μV)
Right sural nerve	Baseline			0.442
	Change
Left sural nerve	Baseline			0.332
	Change
Proximal median sensory	Baseline			0.208
	Change
Distal median sensory	Baseline			0.465
	Change
Motor nerve amplitude (mV)
Proximal median motor	Baseline			0.026
	Change
Distal median motor	Baseline			0.019
	Change
Proximal tibial motor	Baseline			0.477
	Change
Distal tibial motor	Baseline			0.821
	Change

Data shown are mean ± SD change from baseline to last observation carried forward. values were obtained from an ANCOVA model with change from baseline to the last observation and the baseline value as a covariate.