The Type 2 Deiodinase Thr92Ala Polymorphism Is Associated with Worse Glycemic Control in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis

Table 1

Characteristics of selected studies.

Author name	Year	Country	DM	Treatment	Ala/Ala subjects ()			Non-Ala/Ala subjects ()			Ala allele frequency	NOS scale
			Duration (year)		(%)	Age	Male (%)	(%)	Age	Male (%)
Canani	2005	Brazil	11.4 ± 8.6	Diet alone/anti-DM drugs	35 (19.1)	58.0 ± 9.8	45.7	148 (80.9)	58.1 ± 10.9	42.6	0.41	7
Dora	2010	Brazil	10 (5–17)	Insulin/anti-DM drugs	173 (16.4)	46.9 ± 10.7	43.4	884 (83.6)	47.5 ± 11.0	48.0	0.38	7
Dhanunjaya	2015	India	NS	NS	80 (33.9)	60.0 ± 9.0	100.0	156 (66.1)	57.0 ± 10	100.0	0.60	6
Estivalet	2011	Brazil	12.1 ± 9.4	Diet alone/anti-DM drugs/insulin  &  anti-DM drugs	110 (15.4)	58.3 ± 9.4	41.4	604 (84.6)	60.7 ± 9.7	48.9	0.39	7