Journal of Diabetes Research / 2016 / Article / Tab 1

Research Article

The Expression of miR-192 and Its Significance in Diabetic Nephropathy Patients with Different Urine Albumin Creatinine Ratio

Table 1

Clinical characteristics of the subjects.

NCNAMALA

Age (years)51.33 ± 9.1651.4 ± 8.5755.40 ± 12.0658.33 ± 9.04
Duration (years)5.03 ± 1.278.21 ± 0.99b11.53 ± 1.05bc
BMI (Kg/m2)23.76 ± 1.6026.49 ± 1.36a25.30 ± 1.81a25.31 ± 1.81a
SBP (mmHg)115.51 ± 3.22125.72 ± 3.43a130.43 ± 3.04ab136.49 ± 4.78abc
DBP (mmHg)75.13 ± 2.6477.67 ± 3.35a80.21 ± 2.17ab82.84 ± 1.73abc
HbA1C (%)5.16 ± 0.248.20 ± 0.12a8.67 ± 0.21b8.89 ± 0.22bc
FBG (mmol/L)5.36 ± 0.478.03 ± 0.60a9.50 ± 0.34ab9.27 ± 0.63ab
PBG (mmol/L)6.52 (6.33–6.83)14.46 (14.17–14.66)a18.66 (15.4621.69)ab16.69 (14.15–19.48)ab
FINS (mIU/L)8.98 (8.42–9.65)6.20 (6.15–6.25)a7.36 (6.32–7.93)ab7.19 (6.37–7.66)ab
PINS (mIU/L)17.04 ± 1.0416.59 ± 1.3718.12 ± 1.13b17.62 ± 1.45b
FCPS (mmol/L)588.26 ± 4.37590.84 ± 2.89531.14 ± 161.08709.38 ± 284.56c
PCPS (mmol/L) 1305.48 (1298.32–1309.87)1388.76 (1383.28–1393.87)a1300.00 (1295.10–1305.80)b1513.70 (1507.60–1517.30)abc
BUN (mmol/L)5.57 ± 1.356.60 ± 0.85a6.55 ± 0.72a7.95 ± 0.33abc
Cr (μmol/L)60.00 (54.00–72.00)60.00 (51.00–73.00)63.00 (57.00–70.00)221.00 (208.00–241.00)abc
CHO (mmol/L)4.62 ± 0.415.03 ± 0.40a5.06 ± 0.33a5.44 ± 0.44abc
TG (mmol/L)1.39 ± 0.161.57 ± 0.05a1.76 ± 0.14ab2.11 ± 2.00abc
LDL-C (mmol/L)2.24 ± 0.193.07 ± 0.22a3.31 ± 0.21ab3.30 ± 0.25ab
HDL-C (mmol/L)1.20 ± 0.011.50 ± 0.02a1.00 ± 0.01ab0.80 ± 0.01abc
Ln (UACR) (mmol/L)2.50 ± 0.062.87 ± 0.07a4.88 ± 0.33ab7.11 ± 0.91abc
miR-192 ()
(ng/mg)
1.00 ± 0.020.99 ± 0.010.63 ± 0.01ab0.34 ± 0.01abc
TGF-β1 (ng/mL)6.49 ± 0.2411.61 ± 0.32e20.35 ± 0.97ef28.95 ± 1.28efg
FN (μg/mL)85.67 ± 2.0899.71 ± 2.65e166.8 ± 13.42ef245.83 ± 9.04efg

a: compared with NC group, ; b: compared with NA group, ; c: compared with MA group, ; e: compared with NC group, ; f: compared with MA group, ; g: compared with MA group, . “—” presents no data.
BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; HbA1C: glycated hemoglobin; FBG: fasting blood glucose; PBG: postprandial blood glucose; FINS: fasting insulin; PINS: postprandial insulin; FCPS: fasting C peptides; PCPS: postprandial C peptides; BUN: blood urea nitrogen; Cr: creatinine; CHO: cholesterol; TG: triglyceride; LDL-C: low density lipoprotein cholesterol; HDL-C: high density lipoprotein cholesterol; Ln (UACR): logarithm of urine albumin creatinine ratio; TGF-β1: transforming growth factor; FN: fibronectin.