Research Article

Islet Stellate Cells Isolated from Fibrotic Islet of Goto-Kakizaki Rats Affect Biological Behavior of Beta-Cell

Figure 5

Effects of ISC-SN on insulin mRNA transcript and INS-1 cell function. (a) qRT-PCR analysis of insulin mRNA expression and (b) KSIS assay on INS-1 cells cultured with ISC-SN for 24 h. Insulin mRNA data were normalized by GAPDH gene, and insulin secretion data were normalized by cellular insulin content. Data are expressed as mean ± SE ( to 5), .
(a)
(b)