Taurine Transporter Gene Expression in Mononuclear Blood Cells of Type 1 Diabetes Patients
Table 3
TauT mRNA cell expression and plasma markers of oxidative stress or endothelial function in controls and in type 1 diabetic patients with or without retinopathy.
No retinopathy
Retinopathy
Number
22
13
Duration (yr)
17.50 ± 10.63
26.07 ± 9.37
0.02
HbA1c (%, mmol/mol)
7.77 ± 1.09, 61.50 ± 11.98
8.07 ± 1.04, 64.77 ± 11.38
NS
Plasma taurine (µmol/L)
46.49 (23.79)
49.23 (18.58)
NS
Intracellular taurine (nmol/106 cells)
63.19 (32.73)
43.34 (42.06)
NS
Plasma arginine (µmol/L)
84.04 (16.72)
82.95 (44.71)
NS
Plasma homocysteine (µmol/L)
10.90 (4.97)
13.1 (5.20)
NS
Asymmetric dimethylarginine (µmol/L)
0.57 (0.13)
0.56 (0.10)
NS
Symmetric dimethylarginine (µmol/L)
0.51 (0.15)
0.53 (0.22)
NS
Malonyldialdehyde (µmol/L)
4.27 (1.71)
4.49 (1.83)
NS
Cellular carbonyls (nmol/mg)
1.22 (0.62)
1.50 (0.49)
NS
TauT mRNA gene expression ()
1.36 (0.34)
1.16 (0.20)
0.02
Data are shown as median (interquartile range) or mean ± SD.
