Research Article

Implication of Cytotoxic Helicobacter pylori Infection in Autoimmune Diabetes

Table 1

Unadjusted odds ratio and 95% confidence interval for frequency of H. pylori antibodies in the adult population according to the three study groups: late-onset type 1 diabetes, latent autoimmune diabetes, and type 2 diabetes, stratified by birth cohorts.

VariableType 1
Number (Hp%)
OR@ (95% CI)LADA
Number (Hp%)
OR@ (95% CI)Type 2
Number (Hp%)

Birth cohort (y)
1 (100)14 (43)0
 1930–193919 (68) 3.25 (0.43–24.84)52 (53)1.62 (0.25–10.51)5 (40)
 1940–194924 (50)0.68 (0.27–1.69)86 (58)0.86 (0.47–1.58)84 (54)
 1950–195924 (42)0.63 (0.24–1.69)50 (50)0.82 (0.37–1.80)48 (50)
 1960–196923 (39)1.93 (0.47–7.88)30 (47)2.63 (0.69–10.02)15 (27)
14 (14)6 (33)4 (0)
 Total105 (45)0.75 (0.46–1.23)234 (52)0.96 (0.64–1.43)156 (49)

Gender
 Male55 (44)0.74 (0.37–1.46)108 (52)1.01 (0.57–1.78)85 (54)
 Female50 (46)0.95 (0.46–1.96)126 (52)1.14 (0.64–2.02)71 (46)

Percentage positive for Helicobacter pylori infection.
@Odds ratio; confidence interval.