Implication of Cytotoxic Helicobacter pylori Infection in Autoimmune Diabetes
Table 1
Unadjusted odds ratio and 95% confidence interval for frequency of H. pylori antibodies in the adult population according to the three study groups: late-onset type 1 diabetes, latent autoimmune diabetes, and type 2 diabetes, stratified by birth cohorts.
Variable
Type 1 Number (Hp%)
OR@ (95% CI†)
LADA Number (Hp%)
OR@ (95% CI†)
Type 2 Number (Hp%)
Birth cohort (y)
1 (100)
—
14 (43)
—
0
1930–1939
19 (68)
3.25 (0.43–24.84)
52 (53)
1.62 (0.25–10.51)
5 (40)
1940–1949
24 (50)
0.68 (0.27–1.69)
86 (58)
0.86 (0.47–1.58)
84 (54)
1950–1959
24 (42)
0.63 (0.24–1.69)
50 (50)
0.82 (0.37–1.80)
48 (50)
1960–1969
23 (39)
1.93 (0.47–7.88)
30 (47)
2.63 (0.69–10.02)
15 (27)
14 (14)
—
6 (33)
—
4 (0)
Total
105 (45)
0.75 (0.46–1.23)
234 (52)
0.96 (0.64–1.43)
156 (49)
Gender
Male
55 (44)
0.74 (0.37–1.46)
108 (52)
1.01 (0.57–1.78)
85 (54)
Female
50 (46)
0.95 (0.46–1.96)
126 (52)
1.14 (0.64–2.02)
71 (46)
Percentage positive for Helicobacter pylori infection. @Odds ratio; †confidence interval.