The IL-1β Receptor Antagonist SER140 Postpones the Onset of Diabetes in Female Nonobese Diabetic Mice

Table 2

The effect of diabetic state and compound administration.

	β-cell mass		Non-β-cell mass		Non-IR endocrine cells
	-value	value	-value	value	-value	value
Treatment	0.22	0.64	2.25	0.14	1.02	0.32
Diabetic state	20.69	<0.0001	16.74	<0.001	7.52	<0.01
Interaction	0.71	0.41	0.065	0.80	6.26	0.018
	Total endocrine mass		Immune cell mass
	-value	value	-value	value
Treatment	0.73	0.40	1.39	0.25
Diabetic state	17.64	<0.001	5.74	0.02
Interaction	0.068	0.80	1.34	0.26

Statistical outcomes of 2 × 2 factorial ANOVA. Results from two-way ANOVA (diabetic state and treatment) are shown with - and values.