TY - JOUR
A2 - Yao, Xinghai
AU - Uyar, Seyit
AU - Balkarlı, Ayşe
AU - Erol, Muhammet Kazım
AU - Yeşil, Bayram
AU - Tokuç, Abdullah
AU - Durmaz, Doğan
AU - Görar, Süheyla
AU - Çekin, Ayhan Hilmi
PY - 2016
DA - 2016/12/13
TI - Assessment of the Relationship between Diabetic Retinopathy and Nailfold Capillaries in Type 2 Diabetics with a Noninvasive Method: Nailfold Videocapillaroscopy
SP - 7592402
VL - 2016
AB - Background and Objectives. Nailfold capillaroscopy is an easy and noninvasive technique used to investigate dermal microvasculature. Traditional investigations of vascularity do not detect changes until they are well-established in type 2 diabetics. The objective of the current study was to evaluate nailfold capillaries in type 2 diabetes mellitus patients and to determine the association of retinopathy with changes in the nailfold capillaries. Materials and Methods. Capillaroscopic findings by nailfold capillaroscopy and fundoscopic examinations were assessed in 216 patients with type 2 diabetes mellitus and 101 healthy controls included in this prospective study. Results. Retinopathy was detected in 43.05% of diabetic patients (n=93). Capillaroscopic findings including tortuosity (p<0.001), bushy capillary (p<0.001), neoformation (p<0.001), bizarre capillary (p<0.001), microhemorrhage (p=0.001), capillary ectasia (p=0.002), and aneurysm (p=0.004) were significantly higher in diabetic group than control group. In logistic regression analysis, only tortuosity was shown significant (OR, 2.16; p=0.036). There was also a significant relation between diabetes duration and most of the capillaroscopic findings. Conclusion. Capillaroscopic changes were found to be correlated with diabetic retinopathy, in particular with longer disease duration in our study. Capillaroscopic imaging could be a useful new technique for assessment of diabetic microvascular changes.
SN - 2314-6745
UR - https://doi.org/10.1155/2016/7592402
DO - 10.1155/2016/7592402
JF - Journal of Diabetes Research
PB - Hindawi Publishing Corporation
KW -
ER -