Research Article
miRNAs in Urine Extracellular Vesicles as Predictors of Early-Stage Diabetic Nephropathy
Table 1
Demographic characteristics of subjects.
| | Normo. () | Micro. () | Macro. () |
| Age (years) | 57.90 ± 1.50 | 59.00 ± 1.84 | 55.00 ± 1.81 | Sex, male/female | 27/3 | 27/3 | 17/3 | Duration of diabetes (years) | 7.08 ± 1.15 | 8.74 ± 1.26 | 8.33 ± 1.65 | BMI | 24.76 ± 0.61 | 24.26 ± 0.48 | 25.47 ± 0.61 | SBP (mmHg) | 136 ± 4.17 | 139.93 ± 3.22 | 149.8 ± 5.03 | DBP (mmHg) | 82.23 ± 1.94 | 85.67 ± 2.16 | 90.5 ± 3.29 | HbA1C, % | 9.43 ± 0.42 | 9.50 ± 0.34 | 9.47 ± 0.38 | Scr (mol/L) | 74.47 ± 2.72 | 78.87 ± 3.35 | 91.1 ± 8.11 | Cystatin (mg/L) | 0.98 ± 0.04 | 1.22 ± 0.08 | 1.44 ± 0.12 | TC (mmol/L) | 4.87 ± 0.16 | 4.75 ± 0.17 | 4.53 ± 0.21 | TGs (mmol/L) | 1.31 ± 0.09 | 1.67 ± 0.20 | 2.82 ± 0.40 | HDL-C (mmol/L) | 1.00 ± 0.03 | 0.97 ± 0.24 | 0.99 ± 0.26 | LDL-C (mmol/L) | 3.11 ± 0.16 | 3.08 ± 0.17 | 2.75 ± 0.17 | eGFR (mL/min/1.73 m2) | 94.78 ± 2.86 | 87.45 ± 3.57 | 86.82 ± 5.96 | UACR (mg/mmol) | 0.98 ± 0.10 | 17.07 ± 3.44 | 210.02 ± 49.49 | UAER (mg/24 h) | 9.44 ± 0.74 | 145.47 ± 14.42 | 1742.8 ± 371.14 |
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Data are expressed as means ± SE. Normo.: normoalbuminuria; micro.: microalbuminuria; macro.: macroalbuminuria; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; HbA1C: glycosylated hemoglobin; Scr: serum creatinine; TC: cholesterol; TGs: triglycerides; HDL-C: high-density lipoprotein-cholesterol; LDL-C: low-density lipoprotein-cholesterol; eGFR: estimated glomerular filtration rate; UACR: urinary albumin/creatinine ratio; UAER: urinary albumin excretion rate. values were calculated by Student’s -test. versus normo. group; versus micro. group.
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