Novel Association of WNK4 Gene, Ala589Ser Polymorphism in Essential Hypertension, and Type 2 Diabetes Mellitus in Malaysia

Table 2

Genotype and allelic frequency distribution between hypertensive and normotensive subjects.

	Hypertensive subjects	Normotensive subjects	value
Genotype
GG	95 (58.3)	109 (69.4)	0.005
TG	57 (35.0)	48 (30.6)
TT	11 (6.7)	0 (0.0)
Allele frequency
G	247 (75.8)	266 (84.7)	0.015
T	79 (24.2)	48 (15.3)
Post hoc test	value	(95% confidence interval)
TT versus TG	0.004	0.15–0.76
TT versus GG	0.001	0.23–0.83
TG versus GG	0.193	−0.19–0.4

Significant value () was achieved through Chi-square test as compared with controls. Data were reported in number with percent in parentheses. EHT in comparison with control subjects.