Research Article
Novel Association of WNK4 Gene, Ala589Ser Polymorphism in Essential Hypertension, and Type 2 Diabetes Mellitus in Malaysia
Table 3
Genotype-clinical characteristics correlations in patients.
| | Variable | GG | GT | TT | value |
| | Gender (male/female) | 52 (54.7%)/43 (45.3%) | 31 (54.4%)/26 (45.6%) | 7 (63.6%)/4 (36.4%) | NS | | Age (year) | 55.63 ± 10.21 | 55.83 ± 10.73 | 60.27 ± 12.49 | NS | | SBP (mm/Hg) | 134.97 ± 21.50 | 135.99 ± 22.02 | 152.73 ± 11.69 | NS | | DBP (mm/Hg) | 80.25 ± 9.81 | 82.87 ± 11.22 | 82.91 ± 10.96 | 0.041 | | BMI (cm/kg) | 25.83 ± 4.93 | 26.24 ± 3.92 | 25.87 ± 4.10 | NS | | FBS (m/mole) | 5.51 ± 1.09 | 5.87 ± 1.31 | 5.87 ± 1.01 | NS | | TCH (m/mole) | 4.87 ± 1.26 | 4.64 ± 0.96 | 4.75 ± 0.72 | NS | | LDL (m/mole) | 3.01 ± 1.13 | 2.82 ± 0.95 | 2.91 ± 0.94 | NS | | HDL (m/mole) | 1.30 ± 0.46 | 1.21 ± 0.36 | 1.34 ± 0.35 | NS | | TG (m/mole) | 1.39 ± 0.56 | 1.38 ± 0.56 | 1.34 ± 0.51 | NS | | Diabetes (no/yes) | 46 (48.4%)/49 (51.6%) | 22 (38.6%)/35 (61.4%) | 7 (77%)/4 (44%) | NS | | Family history (no/yes) | 42 (44.7%)/52 (55.3%) | 23 (40.4%)/34 (50.6%) | 8 (72.7%)/3 (27.3%) | NS | | Smoking habit (no/yes) | 77 (81.1%)/18 (18.9%) | 48 (84.2%)/9 (15.8%) | 8 (72.7%)/3 (27.3%) | 0.045 | | Alcohol consumption (no/yes) | 86 (90.5%)/9 (9.5%) | 44 (77.2%)/13 (22.8%) | 10 (90.9%)/1 (9.1%) | NS |
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Data are presented as mean ± SD; value > 0.05.
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