Novel Association of WNK4 Gene, Ala589Ser Polymorphism in Essential Hypertension, and Type 2 Diabetes Mellitus in Malaysia

Table 4

Genotypes and allele frequencies distribution of gene polymorphisms between two patient groups and control subjects.

	EHT; (%)	EHT+T2DM; (%)	Control; (%)
Genotype and allele frequency
GG	46 (61.3)	49 (55.7)	109 (69.4)
GT	22 (29.3)	35 (39.8)	48 (30.6)
TT	7 (9.3)	4 (4.5)	0 (0)
G	114 (76)	133 (75.6)	266 (84.7)
T	36 (24)	43 (24.4)	48 (15.3)
value	0.001/0.017	0.004/0.009
Odds ratio (95% CI)	571 (252–928)	0.558 (0.352–885)
Post hoc test
TT versus GT	0.000	0.018
TT versus GG	0.000	0.004
GT versus GG	0.790	0.083

value < 0.05.