Research Article

Impaired Albumin Uptake and Processing Promote Albuminuria in OVE26 Diabetic Mice

Figure 4

OVE tubule fluorescence for albumins injected 2 days apart. OVE tubules that retain TR-albumin fluorescence for two days after injection (panel (a)) do not take up FITC-albumin (panel (b)) injected, 5 min before sacrifice. In the merged image (panel (c)) no tubules are double stained. Images were made with a 20x objective and the bar in each panel equals 100 μm.
(a)
(b)
(c)