Exenatide Is an Effective Antihyperglycaemic Agent in a Mouse Model of Wolfram Syndrome 1

Figure 6

Effect of treatment with exenatide during IPGGT on insulin-to-glucose ratio. Wfs1^+/+, white bars; Wfs1^+/−, grey bars; Wfs1^−/−, black bars. To compare the glucose-insulin ratio between baseline (−30 min) and the 60-minute time point, repeated measures ANOVA was used, followed by the Duncan post hoc test, where versus baseline; versus baseline. To compare the treatment effect at the 60-minute time point, two-way ANOVA was used, followed by the Duncan post hoc test, where versus saline at the same time point; versus saline at the same time point. in all groups.