Assessment of Insulin Resistance in Subjects with Normal Glucose Tolerance, Hyperinsulinemia with Normal Blood Glucose Tolerance, Impaired Glucose Tolerance, and Newly Diagnosed Type 2 Diabetes (Prediabetes Insulin Resistance Research)
Table 3
Baseline data of the subjects—mean ± SE ().
NGT ()
HINS ()
IGT ()
T2DM ()
Age (years)
44.40 ± 11.74
43.36 ± 11.24
45.56 ± 9.83
44.40 ± 8.18
0.77
Gender (F/M)
1/4
4/21
4/21
5/20
0.99
BMI (kg/m2)
22.41 ± 1.54
27.26 ± 3.60
27.38 ± 3.57
26.49 ± 3.52
0.043
Waist (cm)
76.75 ± 7.72
89.71 ± 10.92
91.26 ± 9.85
91.68 ± 10.00
0.057
WHR
0.90 ± 0.11
0.94 ± 0.10
0.93 ± 0.06
0.95 ± 0.06
0.52
SBP (mmHg)
124.50 ± 11.82
124.92 ± 12.03
120.76 ± 12.15
126.32 ± 16.04
0.63
DBP (mmHg)
74.00 ± 7.30
79.88 ± 6.95
80.08 ± 9.24
78.36 ± 10.85
0.56
TG (mmol/L)
1.24 ± 0.73
2.40 ± 1.43
2.05 ± 1.16
1.77 ± 0.81
0.13
HDL (mmol/L)
1.62 ± 0.35
1.38 ± 0.32
1.21 ± 0.38
1.06 ± 0.21
0.000
LDL (mmol/L)
2.67 ± 0.67
2.68 ± 0.61
2.95 ± 0.89
3.14 ± 0.80
0.175
TC (mmol/L)
4.89 ± 0.54
5.44 ± 0.80
4.83 ± 0.87
4.97 ± 0.88
0.15
Glu 0 (mmol/L)
4.89 ± 0.59
4.95 ± 0.43
5.39 ± 0.60
8.09 ± 1.67
0.000
Glu 120 (mmol/L)
5.58 ± 1.40
6.22 ± 1.00
8.92 ± 1.06
13.15 ± 3.62
0.000
FINS (mU/L)
5.29 ± 4.61
11.69 ± 5.98
11.87 ± 6.80
8.79 ± 6.59
0.029
ALB/CR (mg/g)
10.50 ± 3.54
10.57 ± 6.86
20.69 ± 18.05
15.90 ± 20.68
0.756
HbA1c (%)
—
—
5.59 ± 0.35
8.02 ± 2.03
0.000
value (mg⋅kg−1⋅min−1)
Notes: differences among the four groups were compared using analysis of variance (ANOVA) or the Kruskal-Wallis test; the values were shown in the right column. Then we compare each parameter between any two patient groups, , compared with NGT, , compared with HINS, and , compared with IGT.