Assessment of Insulin Resistance in Subjects with Normal Glucose Tolerance, Hyperinsulinemia with Normal Blood Glucose Tolerance, Impaired Glucose Tolerance, and Newly Diagnosed Type 2 Diabetes (Prediabetes Insulin Resistance Research)

Table 9

Assessment of islet beta cell function and other simple insulin sensitivity indexes—mean ± SE ().

	NGT	HINS	IGT	T2DM
FINS	5.29 ± 4.61	11.69 ± 5.98	11.87 ± 6.80	8.79 ± 6.59	0.029
FINS/FBG	1.02 ± 0.75	2.37 ± 1.22	2.27 ± 1.34	1.15 ± 0.89	0.001
HOMA-IR	0.99 ± 1.21	2.59 ± 1.38	2.78 ± 1.57	3.07 ± 2.29	0.006
QUICKI	0.40 ± 0.05	0.34 ± 0.04	0.34 ± 0.03	0.34 ± 0.03	0.016
Matsuda index	13.16 ± 7.24	4.86 ± 1.95	6.38 ± 3.75	6.24 ± 3.58	0.0005
Gutt index	5.10 ± 1.29	3.62 ± 0.59	3.48 ± 0.0.80	2.77 ± 0.95	0.000
HOMA-β	70.32 ± 32.43	176.96 ± 115.28	143.89 ± 93.47	44.11 ± 35.50	0.000
Disposition index	77.34 ± 34.56	71.23 ± 29.44	50.40 ± 19.69	14.76 ± 7.07	0.000
Insulinogenic index	69.02 ± 75.94	99.26 ± 96.58	15.68 ± 18.04	8.56 ± 7.20	0.000
value					0.005

Notes: differences among the four groups were compared using analysis of variance (ANOVA) or the Kruskal-Wallis test; the values were shown in the right column. Then we compare each parameter between any two patient groups, , compared with NGT, , compared with HINS, and , compared with IGT.