Risk Factors for the Requirement of Antenatal Insulin Treatment in Gestational Diabetes Mellitus
Table 1
Characteristics of GDM.
AIT group ()
Diet group ()
value
Gestational age at diagnosis (years)
33.8 ± 7.0
35.7 ± 3.6
0.284
Gestational weeks at diagnosis (weeks)
18.9 ± 2.0
21.6 ± 4.1
0.053
Twins, (%)
2 (20.0)
1 (3.7)
0.107
Family history of diabetes mellitus, (%)
7 (70.0)
16 (59.3)
0.550
Pregestational BMI (kg/m2)
24.5 ± 4.8
23.0 ± 4.4
0.383
95% CI
21.0–27.9
21.3–24.7
<20.0 (%)
20.0
14.8
20–24.9 (%)
40.0
59.3
25–29.9 (%)
30.0
18.5
≥30.0 (%)
10.0
7.4
Infertility treatment, (%)
4 (40.0)
12 (44.4)
0.809
Treatment of preterm labor with ritodrine, (%)
4 (40.0)
4 (14.8)
0.098
Maximal glucose levels during ritodrine treatment (mmol/L)
9.0 ± 1.2
7.3 ± 0.7
0.062
Prior gestational diabetes, (%)
1 (10.0)
5 (18.5)
0.532
Primipara, (%)
5 (50.0)
12 (44.4)
0.763
Plasma glucose level (mmol/L)
Fasting
4.82 ± 0.49
4.69 ± 0.46
0.465
At 1 hr
10.86 ± 0.62
9.19 ± 1.57
0.003
At 2 hr
9.43 ± 1.56
7.96 ± 1.37
0.008
Number of abnormal values,
1.9 ± 0.6
1.26 ± 0.4
0.001
HbA1c (%)
5.3 ± 0.3
5.2 ± 0.4
0.234
Gestational weeks at start of AIT (weeks)
26.1 ± 5.9
The maximum of insulin dose (units/day)
10 ± 5.5
AIT, antenatal insulin treatment; BMI, body mass index; CI, confidence interval; and HbA1c, hemoglobin A1c. Data are shown as mean ± SD or . By Student’s t-test. By Chi-square test. At the time of the 75 g oral glucose tolerance test. After the administration of 75 g of glucose.
