Clinical Study

Comparison of the Effects of Continuous Subcutaneous Insulin Infusion and Add-On Therapy with Sitagliptin in Patients with Newly Diagnosed Type 2 Diabetes Mellitus

Table 1

Baseline comparisons between the CSII and CSII + Sig groups before treatment.

CharacteristicGroup value
CSIICSII + Sig

Patients3030
Gender (F/M)15/1516/14
Age (years)45.18 ± 7.1046.40 ± 5.140.49
Weight (kg)63.14 ± 6.4565.99 ± 9.900.19
BMI (kg/m2)23.56 ± 1.4823.76 ± 3.010.74
HbA1c (%)10.06 ± 1.8210.47 ± 1.330.32
GA (%)33.42 ± 4.6834.11 ± 3.860.53
FPG (mmol/L)10.39 ± 0.9610.23 ± 0.920.50
PPG (mmol/L)17.97 ± 1.4818.52 ± 1.450.15
FC-P (ng/mL)1.65 ± 0.591.48 ± 0.710.32
PC-P (ng/mL)3.99 ± 2.144.20 ± 1.700.67
CPI0.89 ± 0.330.82 ± 0.420.49
SUIT2.26 ± 0.842.09 ± 1.070.49
TC (mmol/L)5.17 ± 0.725.25 ± 0.650.69
HDL-C (mmol/L)1.35 ± 0.291.40 ± 0.270.50
LDL-C (mmol/L)2.78 ± 0.642.90 ± 0.770.51
Tg (mmol/L)1.94 ± 0.622.06 ± 0.960.57

Note: data are presented as the means ± SD. CSII group: CSII monotherapy group; CSII + Sig group: CSII therapy in combination with sitagliptin group; GA: glycated albumin; FPG: fasting plasma glucose; PPG: postprandial plasma glucose; FC-P: fasting C-peptide; PC-P: 2-h postprandial C-peptide; CPI: C-peptide reactivity index; SUIT: secretory unit of islet in transplantation index; TC: total cholesterol; Tg: triglycerides; HDL-C: high-density lipoprotein-cholesterol; LDL-C: low-density lipoprotein-cholesterol.