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Journal of Diabetes Research
Volume 2017 (2017), Article ID 1708148, 9 pages
https://doi.org/10.1155/2017/1708148
Clinical Study

Impact of ELKa, the Electronic Device for Prandial Insulin Dose Calculation, on Metabolic Control in Children and Adolescents with Type 1 Diabetes Mellitus: A Randomized Controlled Trial

Pediatric Hospital, Department of Pediatrics and Pediatric Diabetes, Warszawski Uniwersytet Medyczny, Ul. Żwirki i Wigury 63A, 02-091 Warsaw, Poland

Correspondence should be addressed to Agnieszka Szypowska; moc.liamg@akswopyzs.akzseinga

Received 14 July 2016; Revised 26 November 2016; Accepted 15 December 2016; Published 23 January 2017

Academic Editor: Brunella Capaldo

Copyright © 2017 Agnieszka Kowalska et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. The ELKa system is composed of computer software, with a database of nutrients, and a dedicated USB kitchen scale. It was designed to automatize the everyday calculations of food exchanges and prandial insulin doses. Aim. To investigate the influence of the ELKa on metabolic control in children with type 1 diabetes mellitus (T1DM). Methods. A randomized, parallel, open-label clinical trial involved 106 patients aged <18 years with T1DM, , undergoing intensive insulin therapy, allocated to the intervention group, who used the ELKa (), or the control group (), who used conventional calculation methods. Results. After the 26-week follow-up, the intention-to-treat analysis showed no differences to all endpoints. In per protocol analysis, 22/53 (41.5%) patients reporting ELKa usage for >50% of meals achieved lower levels (), lower basal insulin amounts (), and lower intrasubject standard deviation of blood glucose levels () in comparison with the control. Moreover, in the intervention group, significant reduction of level, by 0.55% point (), was noted. No intergroup differences were found in the hypoglycemic episodes, BMI-SDS, bolus insulin dosage, and total daily insulin dosage. Conclusions. The ELKa system improves metabolic control in children with T1DM under regular usage. The trial is registered at ClinicalTrials.gov, number NCT02194517.