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Journal of Diabetes Research
Volume 2017, Article ID 2195059, 10 pages
https://doi.org/10.1155/2017/2195059
Review Article

The Association of Haptoglobin Gene Variants and Retinopathy in Type 2 Diabetic Patients: A Meta-Analysis

1Department of Medical Informatics, Medical School of Nantong University, Nantong 226001, China
2Department of Biomedical Engineering, University of Southern California, Los Angeles, CA 90089, USA
3Department of Endocrinology, Affiliated Hospital of Nantong University, Nantong 226001, China

Correspondence should be addressed to Kui Jiang; nc.ude.utn@jiuk

Received 25 February 2017; Accepted 23 May 2017; Published 3 July 2017

Academic Editor: Andrea Flex

Copyright © 2017 Huiqun Wu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. A. Chadli, S. El Aziz, N. El Ansari et al., “Management of diabetes in Morocco: results of the International Diabetes Management Practices Study (IDMPS) - wave 5,” Therapeutic Advances in Endocrinology and Metabolism, vol. 7, pp. 101–109, 2016. View at Publisher · View at Google Scholar · View at Scopus
  2. A. Phillips, “Optimising the person-centred management of type 2 diabetes,” The British Journal of Nursing, vol. 25, pp. 535–538, 2016. View at Publisher · View at Google Scholar · View at Scopus
  3. M. F. Mahomoodally, A. Mootoosamy, and S. Wambugu, “Traditional therapies used to manage diabetes and related complications in Mauritius: a comparative ethnoreligious study,” Evidence-Based Complementary and Alternative Medicine, vol. 2016, Article ID 4523828, 25 pages, 2016. View at Publisher · View at Google Scholar · View at Scopus
  4. J. A. Beckman and M. A. Creager, “Vascular complications of diabetes,” Circulation Research, vol. 118, pp. 1771–1785, 2016. View at Publisher · View at Google Scholar · View at Scopus
  5. R. Klein and B. E. Klein, “Are individuals with diabetes seeing better? A long-term epidemiological perspective,” Diabetes, vol. 59, pp. 1853–1860, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. R. Klein, M. D. Knudtson, K. E. Lee, R. Gangnon, and B. E. Klein, “The Wisconsin epidemiologic study of diabetic retinopathy: XXII the twenty-five-year progression of retinopathy in persons with type 1 diabetes,” Ophthalmology, vol. 115, pp. 1859–1868, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. E. J. Hollox and L. V. Wain, “Recurrent mutation at the classical haptoglobin structural polymorphism,” Nature Genetics, vol. 48, no. 4, pp. 347-348, 2016. View at Publisher · View at Google Scholar · View at Scopus
  8. L. E. Cahill, M. K. Jensen, S. E. Chiuve et al., “The risk of coronary heart disease associated with glycosylated hemoglobin of 6.5% or greater is pronounced in the haptoglobin 2-2 genotype,” Journal of the American College of Cardiology, vol. 66, no. 16, pp. 1791–1799, 2015. View at Publisher · View at Google Scholar · View at Scopus
  9. Y. C. Chen, C. C. Lee, C. Y. Huang et al., “Haptoglobin polymorphism as a risk factor for chronic kidney disease: a case-control study,” Amercican Journal of Nephrology, vol. 33, no. 6, pp. 510–514, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. J. Staals, B. M. Pieters, I. L. Knottnerus et al., “Haptoglobin polymorphism and lacunar stroke,” Current Neurovascular Research, vol. 5, no. 3, pp. 153–158, 2008. View at Google Scholar
  11. A. A. Amiri, M. B. Hashemi-Soteh, M. R. Haghshenas, F. Daneshvar, A. Rastegar, and T. Farazmand, “Haptoglobin polymorphism in individuals with type 2 diabetic microangiopathy,” North American Journal of Medical Sciences, vol. 5, pp. 529–535, 2013. View at Publisher · View at Google Scholar · View at Scopus
  12. R. Asleh and A. P. Levy, “In vivo and in vitro studies establishing haptoglobin as a major susceptibility gene for diabetic vascular disease,” Vascular Health and Risk Management, vol. 1, pp. 19–28, 2005. View at Publisher · View at Google Scholar · View at Scopus
  13. M. H. Hampe and M. R. Mogarekar, “Haptoglobin2-2 phenotype is an additional risk factor of retinopathy in type 2 diabetes mellitus,” Indian Journal of Human Genetics, vol. 19, pp. 154–158, 2013. View at Google Scholar
  14. G. C. Nitza, G. Merav, D. S. Olga et al., “Does haptoglobin genotype affect early onset of diabetic retinopathy in patients with type 2 diabetes?” Retina, vol. 31, pp. 1574–1580, 2011. View at Google Scholar
  15. M. B. Adinortey, B. A. Gyan, J. P. Adjimani et al., “Haptoglobin polymorphism and association with complications in Ghanaian type 2 diabetic patients,” Indian Journal of Clinical Biochemistry, vol. 26, pp. 366–372, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. V. P. Wobeto, E. T. Rosim, M. B. Melo, L. E. Calliari, and F. Sonati Mde, “Haptoglobin polymorphism and diabetic retinopathy in Brazilian patients,” Diabetes Research and Clinical Practice, vol. 77, pp. 385–388, 2007. View at Publisher · View at Google Scholar · View at Scopus
  17. S. Y. Meng, S. Chen, D. Q. Li, P. Yu, S. J. Zhou, and D. M. Yu, “Association of haptoglobin gene polymorphism with diabetic retinopathy in type 2 diabetes mellitus (A),” Chinese Journal of Diabetes, vol. 19, pp. 325–327, 2011. View at Google Scholar
  18. J. J. Wang, S. Chen, P. Yu, S. Y. Meng, S. J. Zhou, and D. M. Yu, “Association of haptoglobin gene polymorphism with diabetic retinopathy in type 2 diabetes mellitus (B),” Chinese Journal of Diabetes, vol. 19, pp. 329–332, 2011. View at Google Scholar
  19. T. M. Abraham, K. M. Pencina, M. J. Pencina, and C. S. Fox, “Trends in diabetes incidence: the Framingham Heart Study,” Diabetes Care, vol. 38, pp. 482–487, 2015. View at Publisher · View at Google Scholar · View at Scopus
  20. L. S. Geiss, J. Wang, Y. J. Cheng et al., “Prevalence and incidence trends for diagnosed diabetes among adults aged 20 to 79 years, United States, 1980-2012,” JAMA, vol. 312, pp. 1218–1226, 2014. View at Publisher · View at Google Scholar · View at Scopus
  21. Y. W. Chen, Y. Y. Wang, D. Zhao et al., “High prevalence of lower extremity peripheral artery disease in type 2 diabetes patients with proliferative diabetic retinopathy,” PloS One, vol. 10, no. 3, article e0122022, 2015. View at Publisher · View at Google Scholar · View at Scopus
  22. J. M. Tarr, K. Kaul, M. Chopra, E. M. Kohner, and R. Chibber, “Pathophysiology of diabetic retinopathy,” ISRN Ophthalmology, vol. 2013, Article ID 343560, 13 pages, 2013. View at Publisher · View at Google Scholar
  23. H. Kan, J. Stevens, G. Heiss, R. Klein, K. M. Rose, and S. J. London, “Dietary fiber intake and retinal vascular caliber in the atherosclerosis risk in communities study,” The American Journal of Clinical Nutrition, vol. 86, pp. 1626–1632, 2007. View at Google Scholar
  24. L. Wang, T. Y. Wong, A. R. Sharrett, R. Klein, A. R. Folsom, and M. Jerosch-Herold, “Relationship between retinal arteriolar narrowing and myocardial perfusion: multi-ethnic study of atherosclerosis,” Hypertension, vol. 51, pp. 119–126, 2008. View at Publisher · View at Google Scholar · View at Scopus
  25. N. Cheung, F. M. Islam, D. R. Jacobs Jr et al., “Arterial compliance and retinal vascular caliber in cerebrovascular disease,” Annals of Neurology, vol. 62, pp. 618–624, 2007. View at Publisher · View at Google Scholar · View at Scopus
  26. G. Imperatore, R. L. Hanson, D. J. Pettitt, S. Kobes, P. H. Bennett, and W. C. Knowler, “Sib-pair linkage analysis for susceptibility genes for microvascular complications among Pima Indians with type 2 diabetes. Pima diabetes genes group,” Diabetes, vol. 47, pp. 821–830, 1998. View at Publisher · View at Google Scholar · View at Scopus
  27. H. C. Looker, R. G. Nelson, E. Chew et al., “Genome-wide linkage analyses to identify loci for diabetic retinopathy,” Diabetes, vol. 56, pp. 1160–1166, 2007. View at Publisher · View at Google Scholar · View at Scopus
  28. Y. P. Fu, D. M. Hallman, V. H. Gonzalez et al., “Identification of diabetic retinopathy genes through a genome-wide association study among Mexican-Americans from Starr County, Texas,” Journal of Ophthalmology, vol. 2010, 2010. View at Publisher · View at Google Scholar
  29. Y. C. Huang, J. M. Lin, H. J. Lin et al., “Genome-wide association study of diabetic retinopathy in a Taiwanese population,” Ophthalmology, vol. 118, pp. 642–648, 2011. View at Publisher · View at Google Scholar · View at Scopus
  30. T. Awata, H. Yamashita, S. Kurihara et al., “A genome-wide association study for diabetic retinopathy in a Japanese population: potential association with a long intergenic non-coding RNA,” PloS One, vol. 9, no. 11, article e111715, 2014. View at Publisher · View at Google Scholar · View at Scopus
  31. W. H. Sheu, J. Z. Kuo, I. T. Lee et al., “Genome-wide association study in a Chinese population with diabetic retinopathy,” Human Molecular Genetics, vol. 22, pp. 3165–3173, 2013. View at Publisher · View at Google Scholar · View at Scopus
  32. M. A. Grassi, A. Tikhomirov, S. Ramalingam, J. E. Below, N. J. Cox, and D. L. Nicolae, “Genome-wide meta-analysis for severe diabetic retinopathy,” Human Molecular Genetics, vol. 20, pp. 2472–2481, 2011. View at Publisher · View at Google Scholar · View at Scopus
  33. M. MacKellar and D. J. Vigerust, “Role of haptoglobin in health and disease: a focus on diabetes,” Clinical Diabetes, vol. 34, no. 3, pp. 148–157, 2016. View at Publisher · View at Google Scholar
  34. M. J. Nielsen and S. K. Moestrup, “Receptor targeting of hemoglobin mediated by the haptoglobins: roles beyond heme scavenging,” Blood, vol. 114, pp. 764–771, 2009. View at Publisher · View at Google Scholar · View at Scopus
  35. I. Dahan, E. Farber, N. Thauho et al., “Interaction between the haptoglobin 2 phenotype and diabetes mellitus on systolic pulmonary arterial pressure and nitric oxide bioavailability in hemodialysis patients,” Journal of Diabetes Research, vol. 2015, Article ID 613860, 7 pages, 2015. View at Publisher · View at Google Scholar · View at Scopus
  36. J. Watanabe, V. Grijalva, S. Hama et al., “Hemoglobin and its scavenger protein haptoglobin associate with ApoA-1-containing particles and influence the inflammatory properties and function of high density lipoprotein,” The Journal of Biological Chemistry, vol. 284, no. 27, pp. 18292–18301, 2009. View at Publisher · View at Google Scholar · View at Scopus
  37. M. C. Boelter, J. L. Gross, L. H. Canani et al., “Proliferative diabetic retinopathy is associated with microalbuminuria in patients with type 2 diabetes,” Brazilian Journal of Medical and Biological Research, vol. 39, no. 8, pp. 1033–1039, 2006. View at Publisher · View at Google Scholar
  38. F. M. Nakhoul, R. Miller-Lotan, H. Awaad, R. Asleh, and A. P. Levy, “Hypothesis—haptoglobin genotype and diabetic nephropathy,” Nature Clinical Practice Nephrology, vol. 3, pp. 339–344, 2007. View at Publisher · View at Google Scholar · View at Scopus
  39. V. P. Wobeto, P. M. Garcia, T. R. Zaccariotto, and F. Sonati Mde, “Haptoglobin polymorphism and diabetic nephropathy in Brazilian diabetic patients,” Annals of Human Biology, vol. 36, pp. 437–441, 2009. View at Publisher · View at Google Scholar · View at Scopus