Relationship between Metabolic Syndrome and Ocular Microcirculation Shown by Laser Speckle Flowgraphy in a Hospital Setting Devoted to Sleep Apnea Syndrome Diagnostics

Table 6

Results of a single-regression analysis and multiple-regression analysis for factors independently contributing to BOS-Choroid.

Explanatory variables	Single regression		Multiple regression
			Standard regression	value
Age	−0.45	<0.0001	−0.41	−3.47	0.0009
Men = 1, women = 0	0.16	0.17
BMI	−0.05	0.67
Spherical refraction	−0.13	0.27
IOP	0.04	0.77
OPP	−0.001	0.99
Heart rate	0.28	0.01	0.44	4.89	<0.0001
Mean IMT	−0.01	0.95
e’ velocity	0.28	0.01	0.02	0.15	0.88
E/e’ ratio	−0.24	0.04	−0.19	−1.83	0.07
Total cholesterol	−0.03	0.78
LDL-C	0.03	0.80
Hematocrit	0.30	0.009	0.15	1.46	0.15
Creatinine	0.06	0.62
MetS components (0, 1, 2, and 3)	−0.27	0.02	−0.31	−3.41	0.001

Objective variables: BOS-Choroid; , . . BOS: blowout score; BMI: body mass index; IOP: intraocular pressure; OPP: ocular perfusion pressure; IMT: intima-media thickness; LDL-C: low-density lipoprotein cholesterol; HOMA-IR: homeostasis model assessment of insulin resistance; MetS: metabolic syndrome. The correlation coefficient did not show more than 0.6 among the all explanatory variables.