Pirfenidone Accelerates Wound Healing in Chronic Diabetic Foot Ulcers: A Randomized, Double-Blind Controlled Trial
Table 1
Patient baseline demographic and clinical characteristics.
Groups characteristic
Baseline
value
PFD + MDD-O
KTS
Age (years)
57.3 ± 12.6
51.7 ± 9.9
0.069
Gender n (%)
Male 18 (76.9%)
Male 12 (57.7%)
0.139
Female 5 (23.1%)
Female 18 (42.3%)
Years with diabetes
14 ± 9.1
17 ± 10.4
0.416
Months with ulcers
8.6 ± 2.7
6.5 ± 2.2
0.989
Smoking
7 (26.9%)
2 (7.7%)
0.140
Glucose (mg/dL)
139.1 ± 71.7
152.8 ± 85.7
0.597
HDL (mg/dL)
31.4 ± 14.7
38.9 ± 11.8
0.840
VLDL (mg/dL)
27.5 ± 11.6
42.6 ± 40.3
0.211
LDL (mg/dL)
78.9 ± 13.5
101.7 ± 39.1
0.107
Creatinine clearance/24 h (mL/min)
59.9 ± 20.9
74.2 ± 40.8
0.517
Urea (mg/dL)
37.5 ± 24.4
46.0 ± 21.4
0.173
Creatinine (mg/dL)
1.0 ± 0.5
1.6 ± 1.1
0.128
ALT (U/L)
14.4 ± 5.4
25.2 ± 15.4
0.073
AST (U/L)
16.0 ± 3.2
23.4 ± 15.0
0.404
GGT (U/L)
37.1 ± 12.9
90.4 ± 14.5
0.973
VSG (mm/h)
78.1 ± 39.2
64.2 ± 29.2
0.456
The table shows the baseline demographic characteristics of the participants. The groups were homogeneous and comparable at the beginning and end of the trial.
