Changes in the Diaphragm Lipid Content after Administration of Streptozotocin and High-Fat Diet Regime

Table 2

Effects of high-fat diet (HFD), streptozotocin (STZ), and myriocin (M) on diaphragm diacylglycerol content (mean ± SEM, per group). Difference versus Ctrl (); ^#within group difference (M+ versus M−) (). ND: not detected.

	DAG fatty acid composition (nmol/g of wet tissue)
	Ctrl		STZ		HFD
	M−	M+	M−	M+	M−	M+
Myristic acid (14 : 0)	41.16 ± 3.421	33.47 ± 0.945	65.32 ± 5.367	64.19 ± 8.595	59.98 ± 2.605	56.98 ± 3.174
Palmitic acid (16 : 0)	234.9 ± 17.416	226.84 ± 7.371	276.12 ± 21.028	245.71 ± 27.51	324.53 ± 17.959	280.31 ± 7.954
Palmitooleic acid (16 : 1)	28.81 ± 5.212	15.75 ± 1.367	7.58 ± 0.399	7.52 ± 0.797	20.6 ± 1.744	17.22 ± 1.493
Stearic acid (18 : 0)	135.01 ± 13.544	142.8 ± 8.175	189.69 ± 31.681	170.03 ± 21.512	170.38 ± 4.55	164.04 ± 20.206
Oleic acid (18:1n9c)	80.08 ± 7.586	99.81 ± 3.947	82.19 ± 3.315	82.63 ± 6.384	224.42 ± 11.243	179.07 ± 15.183^#
Linoleic acid (18:2n6c)	67.48 ± 3.321	128.42 ± 5.649^#	103.91 ± 3.415	107.32 ± 9.995	197.68 ± 5.589	174.29 ± 12.654
Arachidic acid (20 : 0)	5.4 ± 1.08	4.51 ± 0.267	7.06 ± 0.69	6.81 ± 0.945	7.17 ± 0.836	5.59 ± 0.436
Linolenic acid (C18:9n3)	5.07 ± 0.731	8.2 ± 0.32^#	6.3 ± 0.301	6.74 ± 0.481	10.48 ± 0.33	8.6 ± 0.446^#
Behenic acid (22 : 0)	1.67 ± 0.157	1.71 ± 0.108	3.02 ± 0.211	3.02 ± 0.436	3.27 ± 0.659	2.36 ± 0.272
Arachidonic acid (20:4n6)	7.37 ± 0.925	15.43 ± 0.863^#	13.12 ± 0.868	12.09 ± 0.568	9.86 ± 0.447	11.55 ± 0.663
Lignoceric acid (24 : 0)	4.79 ± 0.566	4.6 ± 0.481	7.93 ± 0.485	8.6 ± 0.39	8.85 ± 2.63	5.86 ± 0.589
Eicosapentaenoic acid (20:5n3)	ND	ND	ND	ND	ND	ND
Nervonic acid (24 : 1)	0.61 ± 0.157	1.64 ± 0.091^#	1.05 ± 0.091	1.25 ± 0.288	1.42 ± 0.32	1.46 ± 0.153
Docosahexaenoic acid (22:6n3)	3.83 ± 0.491	2.46 ± 0.246	5.98 ± 0.39	6.85 ± 0.8	6.35 ± 0.431	6.33 ± 0.56
SAT	422.92 ± 33.997	413.94 ± 12.605	549.14 ± 56.728	498.37 ± 58.127	574.19 ± 15.28	515.13 ± 25.606
UNSAT	193.26 ± 14.719	271.72 ± 9.722^#	220.11 ± 6.939	224.4 ± 18.456	470.82 ± 15.253	398.53 ± 29.846^#
Total	616.18 ± 37.719	685.66 ± 15.206	769.26 ± 57.27	722.77 ± 76.397	1045.01 ± 22.682	913.66 ± 22.965