Prognostic Relevance and Function of MSX2 in Colorectal Cancer

Table 1

Relationship between the MSX2 expression and clinicopathological characteristics of CRC.

Characteristics	Num	MSX2 expression		X^2	P value
		Low	High
Gender				0.275	0.600
Male	81	39	42
Female	55	29	26
Age (years)				2.383	0.123
<60	67	38	29
≥60	69	30	39
Tumor locus				5.024	0.025
Rectum	75	44	31
Colon	61	24	37
Tumor size				4.239	0.040
<4.5 cm	70	39	27
≥4.5 cm	66	29	41
Tumour differentiation				0.762	0.683
Well	17	10	7
Moderate	101	50	51
Poor	18	8	10
Clinical stage				24.846	<0.001
I	27	20	7
II	29	20	9
III	65	25	40
IV	15	3	12
Tumor invasion				8.815	0.003
T1 + T2	28	8	0
T3 + T4	108	13	7
Lymphatic metastasis				14.576	0.010
L0	58	40	18
L1	40	14	26
L2	38	14	24
Distant metastasis				4.533	0.033
Yes	16	4	12
No	120	64	56

Notes. Pearson’s Chi-square test; was defined for statistical significance. Median value.