Research Article
Hepatic Cholesterol-25-Hydroxylase Overexpression Improves Systemic Insulin Sensitivity in Mice
Figure 3
Obese IS mice show higher hepatic Ch25h levels than obese IR mice. (a) Relative Ch25h levels in isolated livers obtained from obese IR and obese IS C57BL/6J mice after 16 weeks on HFD. mRNA levels of hepatic Ch25h levels in obese IS mice were significantly higher comparing to obese IS mice. , per group. (b) Immunoblot analysis of Ch25h protein in isolated livers obtained from obese IR and obese IS C57BL/6J mice after 16 weeks on HFD. For immunoblot β-actin was used as a loading control. , per group.
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