Review Article
Metformin Improves Overall Survival of Colorectal Cancer Patients with Diabetes: A Meta-Analysis
Table 2
Methodological quality of cohort studies included in the meta-analysis.
| | | Quality assessment criteria | Overall quality score (Max = 9) | | selection | Comparability | Outcome | | Representativeness of the exposed cohort | Selection of the nonexposed cohort | Ascertainment of exposure | Demonstration that outcome of interest was not present at start of study | Comparability of cohorts on the basis of the design or analysis | Assessment of outcome | Was follow-up long enough for outcomes to occur | Adequacy of follow-up of cohorts |
| | Spillane et al. | ✴ | ✴ | ✴ | ✴ | ✴✴ | ✴ | ✴ | ✴ | 9 | | Zanders et al. | ✴ | ✴ | ✴ | ✴ | ✴✴ | ✴ | ✴ | ✴ | 9 | | Cossor et al. | ✴ | ✴ | ✴ | ✴ | ✴ | ✴ | — | — | 6 | | Fransgaard et al. | ✴ | ✴ | ✴ | ✴ | ✴✴ | ✴ | ✴ | ✴ | 9 | | Menamin et al. | ✴ | ✴ | ✴ | ✴ | ✴✴ | ✴ | ✴ | ✴ | 9 | | Garrett et al. | ✴ | ✴ | ✴ | ✴ | ✴ | ✴ | ✴ | ✴ | 8 | | Lee et al. | ✴ | ✴ | ✴ | ✴ | ✴✴ | ✴ | — | ✴ | 8 |
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