Diabetes Is Associated with Increased Autoreactivity of Mannan-Binding Lectin

Figure 3

Kidney-to-body weight ratio, albumin-to-creatinine ratio, and kidney glomerulus estimation. (a) Kidney-to-body weight ratio of diabetic C57BL/6J WT mice (), nondiabetic control C57BL/6J WT mice (), diabetic C57BL/6J MBL/DKO mice (), and nondiabetic control C57BL/6J mice MBL/DKO (). (b) Albumin-to-creatinine ratio (AcR) measurements at study end for WT and MBL/DKO mice. (c and d) Light microscope representation of glomerulus from diabetic C57BL/6J MBL/DKO mice (c) and nondiabetic C57BL/6J MBL/DKO control mice (d). (e) Estimation of glomerulus volume in diabetic C57BL/6J MBL/DKO mice () and nondiabetic control C57BL/6J MBL/DKO mice (). Statistical tests are indicated in figure when significant (, , and ). Data is presented as mean (solid line) with SDs (whiskers).

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