The Association between Monocyte Surface CD163 and Insulin Resistance in Patients with Type 2 Diabetes
Table 3
Multiple regression analysis of sCD163, monocyte CD163, and possible clinical factors in insulin resistance by log-transformed HOMA-R values in 166 patients with type 2 diabetes.
Model 1
Model 2
Model 3
β
β
β
Age
0.035
0.775
0.061
0.610
0.026
0.831
Sex (male = 1, female = 0)
0.074
0.505
0.071
0.525
0.065
0.558
BMI
0.308
0.011
0.304
0.012
0.277
0.023
HbA1c
0.063
0.514
0.084
0.381
0.064
0.506
Log [TG]
0.021
0.838
0.025
0.807
0.035
0.736
HDL-C
−0.157
0.120
−0.167
0.106
−0.174
0.090
Cre
0.043
0.704
0.026
0.821
0.024
0.835
Log [hsTNFα]
0.011
0.916
0.024
0.825
0.007
0.946
Log [hsCRP]
0.174
0.137
0.130
0.205
0.113
0.271
Soluble CD163
0.135
0.143
—
—
0.137
0.153
Monocyte CD163
—
—
−0.212
0.025
−0.220
0.020
R2 ()
0.236 (0.003)
0.264 (0.001)
0.281 (0.001)
β: standard correlation coefficient by multiple regression analysis. R2: multiple coefficients of determination. Log: log-transformed TG, FFA, hsTNFα, or hsCRP. The abbreviations are the same as shown in Table 1.
