Forkhead Protein FoxO1 Acts as a Repressor to Inhibit Cell Differentiation in Human Fetal Pancreatic Progenitor Cells

Figure 2

Reduced FoxO1 protein level during induction of human pancreatic progenitor cells. (a) Time course analysis of FoxO1 expression in human pancreatic progenitor cells after induction of differentiation for the time as indicated. Expression of FoxO1 protein was determined by Western blotting. β-Actin was used as loading control. (b) Data were normalized to the level of β-actin and expressed as fold change relative to control. Values are means ± SEM of 3 independent experiments per each group. or , or 0.01.

(a)

(b)