Research Article
Urinary Exosomal MicroRNA Profiling in Incipient Type 2 Diabetic Kidney Disease
Table 1
Clinical and laboratory parameters of patients with type 2 diabetes.
| | Normoalbuminuric DM2 | Macroalbuminuric DM2 |
| | N | 5 | 5 | | Age (years) | 53.40 ± 3.90 | 54.60 ± 2.98 | | Gender (male/female) | 3/2 | 3/2 | | Diabetes duration (years) | 8.00 ± 1.58 | 9.20 ± 1.66 | | SBP (mmHg) | 116.80 ± 4.88 | 118.40 ± 3.70 | | DBP (mmHg) | 76.20 ± 3.07 | 76.60 ± 3.31 | | HbA1C (%) | 8.58 ± 0.76 | 9.20 ± 0.92 | | Body mass index (kg/m2) | 26.18 ± 1.42 | 25.75 ± 2.45 | | Serum creatinine (μmol/L) | 66.4 ± 9.17 | 66.60 ± 7.00 | | eGFR (mL/min × 1.73 m2) | 99.78 ± 8.41 | 100.60 ± 5.38 | | Triglycerides (mmol/L) | 2.10 ± 0.26 | 1.53 ± 0.27 | | Cholesterol (mmol/L) | 5.08 ± 0.36 | 4.78 ± 0.42 | | LDL-C (mmol/L) | 3.32 ± 0.29 | 3.09 ± 0.22 | | HDL-C (mmol/L) | 0.92 ± 0.58 | 1.03 ± 0.15 | | Retinopathy (y/n) | 2/3 | 5/0 | | ACR (mg/mmol) | 0.92 ± 0.35 | 30.90 ± 3.92∗ | | AER (mg/24 h) | 11.60 ± 2.52 | 402.60 ± 24.738∗ |
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Data are shown as mean ± SEM; DM2: type 2 diabetic patients; SBP: systolic blood pressure; DBP: diastolic blood pressure; HbA1C: glycosylated hemoglobin; GFR: glomerular filtration rate; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; ACR: albumin/creatinine ratio; AER: albumin excretion rate; , macroalbuminuric versus normoalbuminuric patients.
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