Diabetes-Induced Reactive Oxygen Species: Mechanism of Their Generation and Role in Renal Injury

Figure 5

Comparison between normal and diabetic glomeruli with regard to pathological events which occurred during onset and progression of diabetes. I, parietal epithelial cells; II, Bowman’s capsule; III, primary urine majorly containing water, urea, electrolytes, glucose, and so forth; IV, podocyte; V, glomerular basement membrane (GBM); VI, endothelial cells; VII, glycocalyx layer; VIII, mesangial cells; IX, extracellular matrix (ECM) proteins.