Journal of Diabetes Research / 2017 / Article / Fig 8

Research Article

db/db Mice Exhibit Features of Human Type 2 Diabetes That Are Not Present in Weight-Matched C57BL/6J Mice Fed a Western Diet

Figure 8

Circulating insulin levels are elevated in both mouse models of obesity, but glucagon is increased only in the db/db mice. Serum insulin (a, b) and glucagon (g, h) in C57BL/6J mice fed either control or Western diet for the indicated number of weeks (a, g) or 14-week-old db/+ and db/db mice (b, h). Serum insulin correlated to body mass or fat mass in C57BL/6J mice fed Western diet for 20 weeks (c and e, resp.) and in 14-week-old db/db mice (d and f, resp.) by Spearman’s correlation. per group; means ± SEM; ; ; . CD: control diet; WD: Western diet.
(a)
(b)
(c)
(d)
(e)
(f)
(g)
(h)

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at help@hindawi.com to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.