Interaction of Pubertal Development and Metabolic Control in Adolescents with Type 1 Diabetes Mellitus

Table 2

Gender-specific HbA1c development in patients with T1DM before and during puberty. Change in HbA1c (%) was calculated by the difference of the HbA1c concentration between the actual and the preceding year.

Age (years)	Δ HbA1c boys	Δ HbA1c girls	value; (Δ HbA1c boys versus girls)
8-9	0.04	0.05	0.05
9-10	0.09	0.07	0.63
10-11	0.06	0.14	0.012
11-12	0.13	0.14	0.065
12-13	0.19	0.16	0.023
13-14	0.19	0.11	0.31
14-15	0.18	0.15	0.23
15-16	0.12	0.24	0.018