Research Article
The CNDP1 (CTG)5 Polymorphism Is Associated with Biopsy-Proven Diabetic Nephropathy, Time on Hemodialysis, and Diabetes Duration
Table 2
Summary of logistic regression analysis of variables predicting biopsy-proven diabetic nephropathy (male and female,
).
| | Univariate analysis | Multivariate analysis | OR | 95% CI | value | OR | 95% CI | value |
| Age (years) | 0.920 | 0.881–0.961 | <0.001 | 0.931 | 0.883–0.980 | 0.007 | BMI (kg/m2) | 0.980 | 0.922–1.041 | 0.513 | — | — | — | Diabetes duration (years) | 0.886 | 0.813–0.966 | 0.006 | 0.895 | 0.812–0.986 | 0.025 | HbA1c (%) | 1.308 | 1.020–1.678 | 0.034 | 1.169 | 0.844–1.619 | 0.348 | Male sex | 2.333 | 0.994–5.477 | 0.052 | 1.957 | 0.748–5.124 | 0.171 | SBP (mmHg) | 1.021 | 1.000–1.042 | 0.052 | 1.024 | 1.001–1.047 | 0.045 | CTG5 homozygosity | 0.353 | 0.127–0.984 | 0.047 | 0.307 | 0.096–0.980 | 0.046 |
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Area under the ROC curve (AUC) = 0.797, for Hosmer-Lemeshow test. BMI: body mass index; SBP: systolic blood pressure.
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