Research Article

Relationships of Insulin Action to Age, Gender, Body Mass Index, and Waist Circumference Present Diversely in Different Glycemic Statuses among Chinese Population

Table 1

Demographics and clinical characteristics of the participants by glycemic status.

Overall ()Previously diagnosed ()Newly diagnosed ()IFG ()NFG () value

Age (years)56.2 (56.1–56.4)60.1 (59.8–60.4)a,b,c57.0 (56.6–57.4)a57.0 (56.7–57.3)a54.8 (54.6–55.1)<0.001
Gender, (male, %)49.4 (49.0–49.8)46.9 (46.7–47.1)a,b,c51.1 (50.9–51.3)a49.4 (49.1–49.6)49.6 (49.4–49.8)<0.001
BMI (kg/m2)24.8 (24.8-24.8)25.7 (25.6–25.8)a25.6 (25.5–25.8)a25.6 (25.5–25.7)a24.1 (24.0-24.1)<0.001
WC (cm)84.8 (84.7–84.9)88.2 (87.9–88.5)a,b87.6 (87.3–88.0)a,b86.9 (86.7–87.2)a82.6 (82.4–82.7)<0.001
WHtR0.53 (0.53-0.53)0.55 (0.54-0.55)a0.54 (0.54-0.55)a0.54 (0.54-0.54)a0.52 (0.51-0.52)<0.001
SBP (mmHg)137.6 (137.4–137.8)142.9 (142.3–143.6)a,b141.9 (141.3–142.6)a141.1 (140.6–141.6)a134.0 (133.7–134.3)<0.001
DBP (mmHg)80.0 (79.9–80.1)80.5 (80.2–80.8)a,b,c82.2 (81.8–82.5)a81.7 (81.4–82.0)a78.7 (78.6–78.9)<0.001
TC (mmol/L)4.9 (4.9-4.9)4.9 (4.9-5.0)a,b,c5.1 (5.1-5.2)a,b5.0 (5.0-5.1)a4.8 (4.8-4.8)<0.001
TG (mmol/L)1.8 (1.7-1.8)2.0 (2.0-2.0)a,c2.3 (2.2-2.3)a,b2.0 (1.9-2.0)a1.5 (1.5-1.5)<0.001
LDL (mmol/L)3.1 (3.1-3.1)3.1 (3.1-3.2)a,b,c3.2 (3.2-3.3)a3.2 (3.2-3.2)a3.0 (3.0-3.0)<0.001
HDL (mmol/L)1.3 (1.2-1.3)1.2 (1.2-1.2)a,b,c1.2 (1.2-1.2)a,b1.2 (1.2-1.3)a1.3 (1.3-1.3)<0.001
FPG (mmol/L)6.3 (6.2-6.3)8.4 (8.3-8.4)a,b,c9.1 (9.0-9.1)a,b6.4 (6.4-6.4)a5.1 (5.1-5.1)<0.001
HbA1c (%)5.5 (5.4-5.5)6.8 (6.7-6.8)a,b6.7 (6.7-6.8)a,b5.5 (5.5-5.5)a4.9 (4.8-4.9)<0.001
HbA1c (mmol/mol)36.1 (35.9–36.2)50.6 (50.0–51.2)50.0 (49.4–50.7)36.5 (36.4–36.7)29.4 (29.3–29.5)
Insulin2.1 (2.0-2.1)2.1 (2.1-2.2)a,b,c2.5 (2.4-2.5)a,b2.3 (2.3-2.3)a1.9 (1.8-1.9)<0.001
HOMA-IR0.7 (0.7-0.8)1.1 (1.1-1.1)a,b,c1.5 (1.5-1.5)a,b1.0 (1.0-1.0)a0.4 (0.1–0.4)<0.001

Mean values (95% confidence interval) or percentages (95% confidence interval) were shown. IFG: impaired fasting glucose; NFG: normal fasting glucose. Insulin and HOMA-IR values were logarithmically transformed. compared with NFG; compared with IFG; compared with newly diagnosed.