Vitamin D Ameliorates Impaired Wound Healing in Streptozotocin-Induced Diabetic Mice by Suppressing Endoplasmic Reticulum Stress

Figure 2

Effect of vitamin D on cell viability: HUVECs were exposed to different conditions for 0, 12, and 24 h. Normal group (200 μg/ml human serum albumin (HAS) and 100 mg/dl glucose); diabetic group (200 μg/ml AGE-HSA and 250 mg/dl glucose); vitamin D treatment group (vitamin D 50 nm, 200 μg/ml AGE-HSA, and 250 mg/dl glucose); and vitamin D antagonist group (vitamin D 50 nm, VDR siRNA 10 nm, 200 μg/ml AGE-HSA, and 250 mg/dl glucose). Cell viability was measured by CCK-8 assay. relative to the VD treatment group. relative to the VD antagonist group.